2 Division of Parasitology, CSIR-CDRI, Lucknow, India. Malaria, Leishmania and Filaria. Close this message to accept cookies or find out how to manage your cookie settings. CDRI Researches on Parasitic Protozoa. doi: 10.1128/AAC.01161-17. Min TH, Khairul MF, Low JH, Che Nasriyyah CH, A'shikin AN, Norazmi MN, Ravichandran M, Raju SS. Downregulation of tufA expression on both mRNA and protein level supports this hypothesis. This study also shows that CLTR increases the concentration of MQ and disrupts the apicoplast. The present study reveals that broad spectrum biological activities (i.e. [1] The society is affiliated to the World Federation of Parasitologists. Print 2018 Jan. Antimalarial interaction of quinine and quinidine with clarithromycin. The division strength in molecular parasitology … Roxithromycin potentiates the effects of chloroquine and mefloquine on multidrug-resistant Plasmodium falciparum in vitro.
S. N. Ghatak, S. Bhattacharji and M. M. Dhar. Epub 2006 Nov 21.
molecular parasitology. Further tufA mRNA/protein expression was investigated to know the effect of both drugs on apicoplast by using qPCR and Western blotting. Parasitology. Malaria, Leishmania and Filaria. Kadian K, Gupta Y, Singh HV, Kempaiah P, Rawat M. Curr Top Med Chem. Significance: [3] It is located in the CDRI campus in Lucknow, in the Indian state of Uttar Pradesh. Dr. VINITA CHATURVEDI. | Immunology and Microbiology of Mycobacterial Infections. [2][3][4] The society was the host of the second Global Meet on Parasitology, held at Hyderabad in 1997. Ed. This site needs JavaScript to work properly. Keywords: Sr. Principal Scientist. Functional Drug targeting approaches, investigating the various immune evasion strategies adopted by the filarial nematode, Immune Cell Signalling in Host-pathogen interactions, Understanding the protein folding and degradation machinery of host and parasite, Leishmania Biology (Visceral Leishmaniasis/Kala-azar), Leishmaniasis comprises a complex of vector-borne diseases, Malaria biology: molecular analyses of parasite organelles, Polypeptides (proteins) and polynucleotides (DNA, RNA) are the most prevalent biological macromolecules, Leishmania cells exist in two morphologically distinct forms, the insect form (promastigotes) is spindle shaped, Sophisticated Analytical Instrument Facility. Many important drugs like mefloquine are not being used because of the development of resistance and other related issues. [7], List of Fellows of the institute updated to 2010[8], Post Graduate Institute of Medical Education and Research, Regional Medical Research Center, Bhubaneswar, "Tribal-dominated districts account for 47% of malaria deaths in India", https://en.wikipedia.org/w/index.php?title=Indian_Society_for_Parasitology&oldid=961834978, All Wikipedia articles written in Indian English, Creative Commons Attribution-ShareAlike License, For exchange of information on Parasitology, This page was last edited on 10 June 2020, at 17:19. [2] The organization serves as a platform for the parasitologists, researchers, biologists and academicians involved in the field of Parasitology related to humans and animals for promoting their activities, exchanging information and disseminating knowledge on the subject. Also, antimalarial a ß – Arteether was developed and licensed to Themis Chemicals Ltd., Mumbai which is in National malaria program and marketed under the trade name E-Mal as an injectable formulation. Epub 2012 Nov 9. The unique feature of this department is that the research teams are involved in drug discovery and development of antiparasitic infections. | Apicoplast; Clarithromycin; Cytochrome P(450); Malaria; Mefloquine. Epub 2019 Aug 5. Apicoplast Metabolism: Parasite's Achilles' Heel. Repurposing Drugs to Fight Hepatic Malaria Parasites.
2011 Aug;138(9):1069-76. doi: 10.1017/S0031182011000850. Epub 2011 Jul 15. 2019 Aug 30;47(4):973-983. doi: 10.1042/BST20170563. Clipboard, Search History, and several other advanced features are temporarily unavailable. Antimicrob Agents Chemother. Singh, Dr. A.B Sen and Dr. G.P Dutta strengthened the foundation of parasite research in India. For over 70 years, this division has played a central role in the growth of molecular parasitology and developed LDH-based diagnosis of malaria, PCR-based diagnostic probe for leishmaniasis and direct agglutination test (DAT) for leishmaniasis. 2017 Dec 21;62(1):e01161-17. Material and methods:
Full text views reflects the number of PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views. Aim: CSIR-CDRI. [2], The society is run by an elected committee and is headed by a president and a secretary; S. L. Hoti[4] and J. K. Saxena being the incumbent office bearers. Scientists of the division have also been part of the team that has received two CSIR Technology awards. Please use the Get access link above for information on how to access this content.
Molecules. CSIR-CDRI. It is evidenced from HPLC data that CLTR might have reduced metabolism of MQ in Plasmodium falciparum, leading to increased levels of MQ to produce enhanced antimalarial activity.
Energy homeostasis is the balance between energy input and expenditure. Usage data cannot currently be displayed. Check if you have access via personal or institutional login, COPYRIGHT: © Cambridge University Press 1988, https://doi.org/10.1017/S0031182000080288. We have explored in vitro interaction of clarithromycin (CLTR), and mefloquine (MQ) against Pf3D7 and PfK1 strains. The Division of Molecular Parasitology and Immunology conducts research on three major human parasitic infections viz. Published online by Cambridge University Press: An abstract is not available for this content so a preview has been provided below. Bioavailability of MQ in parasitized RBC lysate was checked in the presence/absence of CLTR using HPLC method. "PAKISTAN JOURNAL OF PARASITOLOGY" MEMORANDUM OF ASSOCIATION (N.B:This constitution was approved in the 2nd meeting of "Proceedings of Parasitology "held on Wednesday 15th Feb, 2017 at the Old Guest House, University of Karachi, Karachi-75270, Pakistan, after some necessary amendments by the members of the meeting. The metabolism of CLTR is also reduced may be due to competitive metabolism of MQ via CYP3A4. This data will be updated every 24 hours. In the present study, we aimed to control drug resistance by using combination therapy and tried to understand the mechanism involved. Exp Parasitol. Central Drug Research Institute, Lucknow, 1987. The division strength in molecular parasitology and immunology are complemented with expertise in reverse genetics, immune signalling, molecular biology and and biochemistry. Get the latest public health information from CDC: https://www.coronavirus.gov. 81/470) has consistently exhibited broadspectrum anthelmintic efficacy both against adult and larval stages of various helminth parasites of experimental and domestic animals by oral or parenteral route. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Validation of Putative Apicoplast-Targeting Drugs Using a Chemical Supplementation Assay in Cultured Human Malaria Parasites. Functional Genomics and Molecular Toxicology. [5] They organize annual conferences where keynote addresses, award lectures, presentation of research papers, guest lectures and symposia are featured. It has also put in place annual awards such as Young Scientist Award and M. B. Mirza Award for excellence in research paper presentation and publication. antimalarial and antiviral) of MQ can be saved by using suitable partner drug like CLTR. [3], ISP has instituted two oration awards, B. N. Singh Memorial Oration and B. P. Pandey Memorial Oration for honoring excellence in research and teaching respectively. Principal Scientist.
NIH Email your librarian or administrator to recommend adding this journal to your organisation's collection. Principal Scientist .
Workshops and training sessions are also organized regularly for the benefit of young scientists working in Parasitology. The scientific pursuits of eminent parasitologist like Dr. B.N. 3 Division of Pharmaceutics, CSIR-CDRI, Lucknow, India. - Volume 96 Issue 3 CSIR-Central Drug Research Institute, Sector10, Jankipuram Extension, Sitapur Road, Lucknow 226031, Uttar Pradesh, INDIA, Evaluation of new pharmacophores for their blood schizontocidal activity against P.falciparum, Pre-erythrocytic stages of Plasmodium parasites: Basic Biology and The Parasitology Department at Central Drug Research Institute on Academia.edu The unique feature of this department is that the research teams are involved in drug discovery and development of antiparasitic infections. HHS Indian Society for Parasitology is a non profit making registered society formed under the aegis of the Central Drug Research Institute, Lucknow, working as a platform for the parasitologists in India for dissemination of knowledge and exchange of research information. Abstract views reflect the number of visits to the article landing page. 4 Academy of Scientific and Innovative Research … Dr. SABYASACHI SANYAL. NLM MQ and CLTR showed synergism/additiveness (mean ∑FICs = 0.89 and 1.26) against Pf3D7 and PfK1 respectively. [3], The society, besides a quarterly newsletter,[3] publishes a bi-annual journal, Journal of Parasitic Diseases (JPD),[6] the services of which are offered to scientists for publishing their research papers. COVID-19 is an emerging, rapidly evolving situation. The Molecular Parasitology and Immunology Division has been fortunate to have been home to scientists who have earned many coveted national awards among them are Shanti Swaroop Bhatnagar award, Ranbaxy award, INSA young scientist award, Shakuntala Amir Chand award, CSIR young scientist award, Ramalingaswami fellowship, Innovative young Biotechnologist award etc. Dr. AKHILESH K TAMRAKAR. Pandey SK, Dwivedi H, Singh S, Siddiqui WA, Tripathi R. Parasitology. 194 pages. 2013 Mar;140(3):406-13. doi: 10.1017/S003118201200176X. The society is affiliated to the World Federation of Parasitologists.
Please enable it to take advantage of the complete set of features! Copyright © 2015 Elsevier Inc. All rights reserved. CLTR showed its delayed antimalarial effect by its low IC50 values in the second cycle which indicates its effect on apicoplast. Sr. Get the latest research from NIH: https://www.nih.gov/coronavirus. 2018;18(22):1987-1997. doi: 10.2174/1568026619666181130134742. Biochem Soc Trans. Research in this area has led to novel therapeutic drug leads.
[1], Indian Society for Parasitology was established as a registered society under the Indian Societies Act in 1973.
2007 Apr;115(4):387-92. doi: 10.1016/j.exppara.2006.10.004. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error.
This is complemented with the state-of-the-art fundamental research on understanding parasite biology and host immune response. Division of Parasitology, Lucknow-226001, India 抄録 Methyl 5 [4- (2-pyridinyl) -1- piperazinylcarbonyl] -1-H- benzimidazol -2- yl carbamate: (CDRI Comp. This is complemented with the state-of-the-art fundamental research on understanding parasite biology and host immune response. CSIR-CDRI. * Views captured on Cambridge Core between
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