The authors declare that they have no competing interests. [Development of antituberculous drugs: current status and future prospects].
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Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis. Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis. -, Gandhi NR, et al. Impact of pCDs NPs administration on pulmonary homeostasis in mouse. R1���e�)�+R_��Ja#��ut�I�^����r���R�ª��AT�\N��V�)��"4� (, Effect of [ETH:Booster] loaded pCD NPs in a mouse model of. Lancet. 3646 0 obj
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Typical example of NPs encapsulating [ETH:Booster]. 2019 Jan;134:153-165. doi: 10.1016/j.ejpb.2018.10.020. Metabolism of the antituberculosis drug ethionamide. This site needs JavaScript to work properly. Epub 2017 May 15.
2013;31:475–527. Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles . Costa-Gouveia J, Pancani E, Jouny S, Machelart A, Delorme V, Salzano G, Iantomasi R, Piveteau C, Queval CJ, Song OR, Flipo M, Deprez B, Saint-André JP, Hureaux J, Majlessi L, Willand N, Baulard A, Brodin P, Gref R. Sci Rep. 2018 May 10;8(1):7596. doi: 10.1038/s41598-018-25177-2. h�bbd``b`�$k��O �$�O��5 V��R2���@�� ٵ �H� D,b � H0 I) !�$�� i��* ��@B�Hȱ101�t00W��ר+ ���
Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles. | 2019 Apr 23;13(4):3992-4007. doi: 10.1021/acsnano.8b07902. Get the latest public health information from CDC: https://www.coronavirus.gov. Population pharmacokinetics of ethionamide in patients with tuberculosis. ( a…, Intracellular antitubercular activity. The efficacy of the designed formulations was evaluated in TB infected macrophages using an automated confocal high-content screening platform, showing that the drugs maintained their activity after incorporation in NPs. The use of ethionamide (ETH), a main second line anti-TB drug, is hampered by its severe side effects. Phenazine Antibiotic-Inspired Discovery of Bacterial Biofilm-Eradicating Agents. Schematical representation of PLA NPs structure and components. Please enable it to take advantage of the complete set of features! Molecules. This study paves the way for a future use of pCD NPs for the pulmonary delivery of the [ETH:Booster] pair in TB chemotherapy. | Preparation and biological evaluation of ethionamide-mesoporous silicon nanoparticles against Mycobacterium tuberculosis. 2020 Aug 20;64(9):e00713-20.
% of inhibition on bacterial RFU obtained with ETH (solid…, Impact of pCDs NPs administration on pulmonary homeostasis in mouse. 2017 Oct 15;531(2):577-587. doi: 10.1016/j.ijpharm.2017.05.030. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. doi: 10.1016/S0140-6736(10)60410-2.
Epub 2019 Oct 2. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Eur J Pharm Biopharm. Print 2020 Aug 20.
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