You are then treated with high doses of chemotherapy. 2015 Oct;26(10):2125-32. doi: 10.1093/annonc/mdv310. Twenty-three patients received only a single course of HDCT because of progressive disease or toxicity. Long-term sexual functioning in germ-cell tumor survivors. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. Graft-versus-host disease (GvHD) is avoidable with an autologous stem cell transplant, because the cells come from the patient’s own body. Transplant involving one person as both donor and recipient.
Patients and Methods We conducted a retrospective analysis of 364 consecutive patients with GCT who progressed after cisplatin-based combination chemotherapy and were subsequently treated with HDCT and PBSCT.
Using cells from your own body during your stem cell transplant offers some advantages over stem cells from a donor.
There were nine treatment-related deaths. Pico JL, Fadel E, Ibrahim A, Bourhis JH, Droz JP. https://medical-dictionary.thefreedictionary.com/autologous+transplantation. Cox proportional hazards models were used to test predictors of disease progression. Kaplan-Meier estimates of (A) progression-free survival according to line of therapy and (B) platinum sensitivity.
Three hundred forty-one patients received two consecutive courses of HDCT consisting of 700 mg/m2 carboplatin and 750 mg/m2 etoposide, each for 3 consecutive days, and each followed by PBSCT. An autologous stem cell transplant uses healthy blood stem cells from your own body to replace your diseased or damaged bone marrow.
An autologous stem cell transplant uses healthy blood stem cells from your own body to replace your diseased or damaged bone marrow. 2020 Aug 20;20(1):779. doi: 10.1186/s12885-020-07301-6.
NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Chovanec M, Vasilkova L, Petrikova L, Obertova J, Palacka P, Rejlekova K, Sycova-Mila Z, Kalavska K, Svetlovska D, Mladosievicova B, Mardiak J, Mego M. BMC Cancer.
Epub 2019 Jun 1. 2019 May 28;10:318. doi: 10.3389/fendo.2019.00318. Purpose Patients with relapsed metastatic germ cell tumor (GCT) can be cured with second-line and even third-line regimens.
Please enable it to take advantage of the complete set of features! This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. Nieto Y, Tu SM, Bassett R, Jones RB, Gulbis AM, Tannir N, Kingham A, Ledesma C, Margolin K, Holmberg L, Champlin R, Pagliaro L. Ann Oncol. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. / Yeni ilaclarin Doneminde, Multiple Myelomada Kok Hucre Nakli icin Uygun Bir Zamanlama Var midir? Autologous stem-cell transplantation (also called autogenous, autogeneic, or autogenic stem-cell transplantation and abbreviated auto-SCT) is autologous transplantation of stem cells —that is, transplantation in which stem cells (undifferentiated cells from which other cell types develop) are removed from a person, stored, and later given back to that same person.
Complementary & Alternative Medicine (CAM), Coping with Your Feelings During Advanced Cancer, Emotional Support for Young People with Cancer, Young People Facing End-of-Life Care Decisions, Late Effects of Childhood Cancer Treatment, Tech Transfer & Small Business Partnerships, Frederick National Laboratory for Cancer Research, Milestones in Cancer Research and Discovery, Step 1: Application Development & Submission, Supportive & Palliative Care Editorial Board, Levels of Evidence: Supportive & Palliative Care, Levels of Evidence: Screening & Prevention, Levels of Evidence: Integrative Therapies, U.S. Department of Health and Human Services. 2020 Jul;8(14):866. doi: 10.21037/atm-20-654. Get the latest research from NIH: https://www.nih.gov/coronavirus.
Epub 2016 Dec 6. High-dose therapy (HDT) with autologous stem cell transplantation (ASCT) is the standard treatment for patients with chemosensitive relapsed/refractory Hodgkin lymphoma (HL), but this therapy is commonly denied to patients with resistant disease. COVID-19 is an emerging, rapidly evolving situation. Kaplan-Meier estimates of (A) progression-free survival according to line of therapy and (B)…, Kaplan-Meier estimates of progression-free survival…. A general practitioner's guide to hematopoietic stem-cell transplantation. | This site needs JavaScript to work properly. |
Salvage chemotherapy with high-dose carboplatin plus etoposide and autologous peripheral blood stem cell transplant in male pure choriocarcinoma: a retrospective analysis of 13 cases. Autologous transplants allow the use of high-dose chemotherapy, which provides some patients with a better chance of cure or long-term control of their disease. Intensive Care Outcomes of Patients after High Dose Chemotherapy and Subsequent Autologous Stem Cell Transplantation: A Retrospective, Single Centre Analysis. Clipboard, Search History, and several other advanced features are temporarily unavailable. Rancea M, Monsef I, von Tresckow B, Engert A, Skoetz N. Cochrane Database Syst Rev.
Kaplan-Meier estimates of (A) progression-free survival and (B) overall survival for 364 patients. Autologous transplants are used to treat a number of different blood cancers. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. These c…
Using cells from your own body during your stem cell transplant offers some advantages over stem cells from a donor.
Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/.
High-dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin lymphoma. In autologous transplantation, doctors usually collect, or harvest, stem cells that circulate in the bloodstream. A procedure wherein the person donates blood or tissue to themselves. Secondary leukemia developed in five patients.
R01 CA157823/CA/NCI NIH HHS/United States. Neural stem cells & supporting cells--the new therapeutic tools for the treatment of spinal cord injury, Genzyme's Mozobil approved by EU for treating certain cancer patients requiring a stem cell transplant, From then to now: an update on blood and marrow transplantation, An overview of stem cell transplant as a treatment for cancer, automated implantable cardioverter defibrillator, automated medication administration system, Autologous Mixed Lymphocyte-Tumor Culture, Autologous Peripheral Blood Cell Transplantation, autologous peripheral blood mononucleated cells, Autologous Peripheral Blood Progenitor Cell, Autologous Peripheral Blood Progenitor Cell Transplantation, Autologous Peripheral Blood Stem Cell Transplantation, Autologous Peripheral Stem-Cell Transplantation, Autologous Transplantation of Peripheral Blood Precursors, Autologus Blood & Marrow Transplant Registry. See this image and copyright information in PMC.
The high-dose treatment kills the cancer cells, but it also gets rid of the blood-producing cells that are left in your bone marrow. De Padova S, Casadei C, Berardi A, Bertelli T, Filograna A, Cursano MC, Menna C, Burgio SL, Altavilla A, Schepisi G, Prati S, Montalti S, Chovanec M, Banna GL, Grassi L, Mego M, De Giorgi U. Epub 2015 Jul 21. Curr Oncol. PBSC harvesting is similar to giving blood. A generic term for the administration of tissues or cells, in particular bone marrow, which had been removed before high-dose chemo- and/or radiotherapy. Engraftment syndrome (ES) encompasses a continuum of periengraftment complications after autologous hematopoietic stem cell transplantation.
These cells are called peripheral blood stem cells (PBSCs). It is easier than taking cells from a person’s bone marrow, which is sometimes done for allogeneic transplants.
In this procedure, stem cells are collected from the patient and frozen in liquid nitrogen before transplant conditioning.
Most people have a single autologous transplant. 2007 Apr;14(4):336-8. doi: 10.1111/j.1442-2042.2006.01718.x.
Caregiver Emotional Burden in Testicular Cancer Patients: From Patient to Caregiver Support.
An autologous transplant uses a person’s own stem cells. eCollection 2019. Immune-related genes play an important role in the prognosis of patients with testicular germ cell tumor. Autologous versus allogenic transplant. USA.gov.
2007 Aug;40(3):235-7. doi: 10.1038/sj.bmt.1705697. 2017 Feb;14(2):66. doi: 10.1038/nrurol.2016.256. Kaplan-Meier estimates of progression-free survival for seminoma versus nonseminoma. Segen's Medical Dictionary.
An autologous stem cell transplant is also called an autologous bone marrow transplant. Presence of graft versus host disease, delayed immune reconstitution and allogeneic transplantation compared to, There Are No Significant Differences in Cytokines Expression at Day 7 after MDC, Intraspinal transplantation of human [CD34.sup.+] CB cells showed benefit in functional recovery after spinal cord hemisection in rats and suggested that [CD34.sup.+] CB cells might be an excellent choice of cells as a routine starting material of allogenic and, The company says in Europe, Mozobil is indicated in combination with granulocytecolony stimulating factor (G-CSF) to enhance mobilization of stem cells to the blood stream for collection and subsequent, But this strategy ignores certain limitations to, Mildred Pasek, RN, OCN[R], MM, ONS member and DFCI stem cell transplant research nurse, says that the distinguishing features of DFCI's program are its size and age; the availability of autologous, related, and unrelated transplants; the research programs in graft-versus-host prophylaxis and treatment as well as mismatched, double-cord transplants; the vaccine program; and the novel mobilizing agents the program has developed for, Currently, units of UCB from donors with genetic diseases are not indicated for, Dictionary, Encyclopedia and Thesaurus - The Free Dictionary, the webmaster's page for free fun content, Sustained Results in Long-Term Follow-Up of Autologous Chondrocyte Implantation (ACI) for Distal Femur Juvenile Osteochondritis Dissecans (JOCD), Informational theory of aging: the life extension method based on the bone marrow transplantation, Intensive chemotherapy as salvage treatment for solid tumors: focus on germ cell cancer, Hematopoetic stem cell transplantation in children, Dynamics of acute local inflammatory response after autologous transplantation of muscle-derived cells into the skeletal muscle. Kaplan-Meier estimates of (A) progression-free…. Also, it does not require an operation or general anesthesia. Get the latest public health information from CDC: https://www.coronavirus.gov. Kumano M, Miyake H, Hara I, Furukawa J, Takenaka A, Fujisawa M. Int J Urol. High-dose chemotherapy followed by hematological support: experience in the treatment of germ cell tumors.
Is there an optimal timing of autologous stem-cell transplantation for multiple myeloma in the era of novel agents? We report survival outcomes of patients treated with high-dose chemotherapy (HDCT) and peripheral-blood stem-cell transplantation (PBSCT) at Indiana University between 2004 and … High-Dose Chemotherapy and Autologous Peripheral-Blood Stem-Cell Transplantation for Relapsed Metastatic Germ Cell Tumors: The Indiana University Experience J Clin Oncol. Nat Rev Urol. First-line high-dose chemotherapy combined with peripheral blood stem cell transplantation for patients with advanced extragonadal germ cell tumors.
Kaplan-Meier estimates of progression-free survival for primary tumor site: testis/retroperitoneum versus mediastinum. In an autologous transplant, your own blood-forming stem cells are collected. NLM
An autologous transplant is when the donor cells are collected directly from the patient.
2017 Apr 1;35(10):1096-1102. doi: … Bone Marrow Transplant. Afterward, the collected stem cells are put back into your bloodstream, allowing the bone marrow to produce new blood cells.
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