Consult your doctor before breastfeeding. . Whats more, the ADA notes that research on many supplements is inconclusive. Talk to your provider before adding any vitamins or supplements to your regimen. alternatives are covered, and what the copay would be. VA Pharmacy Benefits Management Services, the Medical Advisory Panel and the VISN Pharmacist ExecutivesJanuvia cheap viagra href=viagra online vs Tradjenta comparedmeds.comJanuvia vs Tradjenta. All of these can be helpful, but do not replace the medication your healthcare provider ordered for you. The effects of ACEIs and ARBs on multiple outcomes in type 2 diabetes Januvia (sitagliptin) and Onglyza (saxagliptin) are oral diabetes medicines for people with type 2 diabetes (non-insulin-dependent) diabetes.. Januvia and Onglyza are sometimes used in combination with other diabetes medications, but are not for treating type 1 diabetes.. Side effects of Januvia and Onglyza that are similar include runny or stuffy nose, sore throat, headache, or stomach pain. [2] Since its discovery in 1967, serine protease DPP-4 has been a popular subject of research. Can be taken with or without food. Prescribe generic and formulary medications (see Formulary Alternatives section). The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. At 6 months, adults with an average starting A1C of 8.3% lowered their A1C by an average of: Results are from a 6-month medical study of 1864 adults with type 2 diabetes that compared 7 mg RYBELSUS and 14 mg RYBELSUS with 100 mg JANUVIA when both were added to 1 or 2 diabetes pills. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. February 2014. Another serious side effect is called Fournier gangrene, which can be life-threatening. Januvia is the brand name of Sitagliptin , and is used to treat patients with type 2 diabetes. They are used in the treatment of type 2 diabetes . Interestingly, the modern trend of women living longer than men is reflected in the historic record once the issue of childbirth is factored out; in other words, the same gender advantage that we see in life expectancy trends now was shared by past generations of women once they reached the end of their childbearing years. There are also a few more drugs in this class including the very newly approved Liraglutide (Victoza). Acute pancreatitis, including fatal pancreatitis, has been reported in patients taking TRADJENTA. Januvia. If the reason you are looking for a Januvia alternative is due to side effects or an allergic reaction, then Tradjenta would not be a good alternative, because it is very similar to Januvia and it is very likely you would have the same reaction. Mar 11, 2016 . Sitagliptin + metformin: co-formulated as Janumet 50/500 mg twice a day, with meals. ER -, Your free 1 year of online access expired. In patients taking JENTADUETO XR whose eGFR later falls below 45 mL/min/1.73 m 2, assess benefit risk of continuing therapy. Crcl < 50 Neutral Neutral Neutral Neutral Pancreatitis, liver disease Post prandial Pancreas, liver 350 Sitaglitptin (Januvia) Januvia, Tradjenta, and Onglyza belong to a class of drugs known as dipeptidyl peptidase 4 . Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Everything we do at this amazing site is 100% legal. Januvia 50 Mg. 266/ Stripe Get Latest Price. It is not approved for use in children. Let the pharmacist know that you are switching from. Equivalence was determined by developing a standard Forest plot that incorporated the information on margins previously reported in randomized trials on these agents. U.S. Food and Drug Administration: DPP-4 Inhibitors for Type 2 Diabetes: Drug Safety Communication - May Cause Severe Joint Pain. Five cases were reported with AstraZeneca Plcs Onglyza FDA approves first diabetes-cholesterol combo pill (AP) -- The first combination pill for the millions of people with the dangerous combination of diabetes and high cholesterol won U.S. approval Friday, offering convenience - and savings - to patients taking multiple pills.Juvisync, a probable blockbuster developed by Merck & Co. Inc., will be launched in a few weeks. Overall exposure to the study drug was 2412.8 years for linagliptin and 1481.4 years for placebo (mean [SD], 183 [120] days and 209 [150] days, respectively). Onglyza (saxagliptin) is an add-on medication to diet and exercise to improve blood sugar control in people with type 2 diabetes. Bliard Veillard, R., & Pinto, B. The incretin effect is prolonged, enhancing glycemic control through various mechanisms, primarily by stimulating insulin synthesis and secretion in a glucose-dependant manner and by reducing glucagon secretion. Can be taken with or without food. Lactic acidosis is an emergency and patients having symptoms should seek emergency treatment in the hospital right away. 2018 Standard Formulary Exclusions Drug List Menu. All of these drugs are approved for use in patients with T2D, but are not approved for use in patients with Type 1 diabetes (T1D). Victoza (liraglutide) is an injectable drug that is part of a class called glucagon-like peptide-1 agonists (GLP-1 agonists). , gallstones, or gallbladder inflammation. There are also various oral combination medications available that contain two or more medications: Injectable medications: these are not insulin but help control high blood sugar. DPP-IV inhibitors are FDA approved for use as monotherapy in type 2 diabetes (T2DM). JANUVIA (jah-NEW-vee-ah) es un comprimido de venta bajo receta de una toma por da que, junto con dieta y ejercicio, ayuda a disminuir los niveles de azcar en sangre de adultos con diabetes tipo 2. Can be taken with or without food. It is also approved to lower the risk of major heart events in adults with T2D and heart disease. A generic is not available at this time. The first inhibitors were characterized in the late 1980s and 1990s. We cannot guarantee results and occasional interruptions in updating may occur. FDA approves Trijardy XR (empagliflozin/linagliptin/metformin HCl), a once-daily therapy to lower blood sugar in adults with T2D FDA approves Trijardy XR (empagliflozin/linagliptin/metformin HCl), a once-daily therapy to lower blood sugar in adults with T2D FDA Approves Combination Tablet Trijardy XR | BI US Skip to main content Media Serious hypersensitivity reactions have been reported in patients treated with TRADJENTA including anaphylaxis, angioedema, and exfoliati . Adverse effects of DPP-4 inhibitors include: gastrointestinal problems including nausea, diarrhoea and stomach pain flu-like symptoms headache, runny nose, sore throat skin reactions painful skin followed by a red or purple rash If you have a reaction which causes difficulty breathing or a severe skin reaction, call for medical help. in patients with type 2 diabetes and known cardiovascular disease, and showed that taking sitagliptin for 3 years did not increase or decrease the risk of major adverse cardiovascular events or hospitalization for heart failure. In some cases, patients may be looking for alternative diabetes treatment to Januvia. Orthostatic hypotension, a drop in blood pressure when standing up, is also a potentially serious side effect. 506227 a nivel global segn los datos de Enero 2023. Current treatments , other than insulin supplementation, are sometimes not sufficient to achieve control and may cause undesirable side effects , such as weight gain and hypoglycemia . more Prescription only Ozempic (semaglutide) is also an injectable drug in the, agonist drug class. 05.02.393.1 C (10/18) Covered and non-covered drugs . The occurrence of cardiac disorder AEs was similar in linagliptin- and placebo-treated patients (3.2% [n = 153] and 3.3% [n = 83], respectively); the incidence of heart failure AEs for linagliptin- and placebo-treated patients Dose adjustment of digoxin not recommended, but monitor closely. Biguanides such as metformin are used regularly as a first-line treatment for type 2 diabetes and are the most common medication used for diabetics. It is not insulin. From time-to-time, our system might experience bugs or glitches that affect the accuracy or correct application of mathematical algorithms. Linagliptin: recommended dose is 5 mg once a day. It's FDA-approved for use in adults with type 2 diabetes. The first DPP4 inhibitor on the market was sitagliptin (Januvia). Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. 2.5/1000 mg, 5/1000 mg, or 5/2000 mg once daily with evening meal. So by protecting incretins from damage, DPP-4 inhibitors help regulate blood glucose levels. Tradjenta (linagliptin) tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Januvia (sitagliptin): Meds for control of diabetes very infrequently "cause" weight gain. Includes dose adjustments, warnings and precautions.Januvia and Tradjenta Battle For DPP-4 SupremacyJanuvia is facing increased competition in a market space that seems to be getting evermore crowded. Obtn todos los anlisis de straighthealthcare.com y el desglose de la cuota de mercado aqu To see our formulary, or list of covered drugs, choose your plan from the list below. Given as monotherapy, linagliptin, sitagliptin, and vildagliptin (but not saxagliptin) met the equivalence criterion when compared with one another. Jardiance is approved for three indications: control (along with diet and exercise) in adults with T2D, To lower the risk of cardiovascular death in adults with T2D and heart disease, To lower the risk of cardiovascular death or hospitalization for. This review focuses on gliptins (sitagliptin, vildagliptin, saxagliptin, linagliptin, and alogliptin) discussing pharmacokinetics, pharmacodynamics, efficacy, and. Saxagliptin: recommended dose is 2.5 or 5 mg once a day. Because no head-to-head trials were available comparing . It may be tempting to look at over-the-counter drugs or check the vitamin aisle for a solution to help your blood sugar. Can be taken with or without food. Patients in the saxagliptin groups taking 2.5 mg, 5 mg and 10 mg achieved hemoglobin A1C reductions of 0.43%, 0.46 % and 0.54%, respectively, compared to a 0.19% reduction in the placebo group. It is used together with a healthy diet and regular exercise to control blood sugar levels. The dose is determined by the estimated glomerular. Saxagliptin + metformin XR: co-formulated as Kombiglyze. Or, a serious side effect could occur, such as heart or kidney failure, pancreatitis, joint pain, or a severe skin or allergic reaction. Injectable medications: these are not insulin but help control, would not be a good alternative, because it is very similar to. Linagliptin: rapid absorption; time to peak concentration 1.5 hours. A test calle PCOS is one of the most common hormonal disorders in the developed world. It is unknown if Tradjenta passes into breast milk or if it could harm a nursing baby. Cardiovascular long-term safety data for saxagliptin was investigated in the SAVOR TIMI 53 trial which reported no difference compared to placebo in the rate of ischemic events, however, the rate of hospitalization for heart failure was increased, Among patients with type 2 diabetes with a recent acute coronary syndrome, major adverse cardiovascular events were not increased with alogliptin as compared with placebo, A previous analysis found a 2-fold increased odds of hospitalization for acute pancreatitis in patients using sitagliptin or exenatide. Both have to be taken once per day but in a different quantity. Talk to your doctor about which medications may be most appropriate for you. Study has been completed. Patients taking metformin should be aware of a serious side effect called lactic acidosis. Be sure to include plenty of fruits and vegetables, lean protein, whole grains, and low-fat dairy. With type 2 diabetes, your. Saxagliptin: time to peak concentration 2 hours. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. Weight gain. Advise patients of the symptoms of heart failure and to immediately report such symptoms. DPP-IV inhibitors can also be added to patients already on, GFR 45 mL/min, no dosage adjustment needed, For patients on hemodialysis or peritoneal dialysis, 25 mg daily without regard to timing of hemodialysis, For patients on hemodialysis, administer 2.5 mg once daily, following hemodialysis, GFR 60 mL/min, no dosage adjustment needed, GFR 30 to < 60 mL/minute: 12.5 mg once daily, GFR 15 to < 30 mL/minute: 6.25 mg once daily, ESRD (GFR < 15 mL/minute or requiring hemodialysis): 6.25 mg once daily; administered without regard to timing of hemodialysis, Limited human data - animal data suggest low risk. supplies for the equivalent of two 30 day supply copays. Continue reading >>, Volume 36, Issue 8 , 1 August 2014, Pages 1130-1146 Safety and Tolerability of Linagliptin in Patients With Type 2 Diabetes: A Comprehensive Pooled Analysis of 22 Placebo-controlled Studies Dipeptidyl peptidase (DPP)-4 inhibitors are an increasingly used antihyperglycemic therapy for patients with type 2 diabetes mellitus (T2DM). Januvia may interact with digoxin, probenecid, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers. The incidence of neoplastic AEs was low (0.6% and 0.9%, respectively); there were no reports of pancreatic neoplasia. is used along with diet and exercise to improve, control in adults with T2D. Or you can search our formulary online (courtesy of Lexicomp). Pharmacodynamics: Comment: The SAVOR- TIMI 53 showed that in patients with type 2 diabetessaxagliptin did not increase or decrease the rate of ischemic events, though the rate of hospitalization for heart failure was increased. showed that in patients with type 2 diabetes. *General dosing is listed. Exercise is helpful in controlling blood sugar as well. Saxagliptin: 2.5 or 5 mg once a day. Januvia (sitagliptin) is an add-on medication to diet and exercise to improve blood sugar control in people with type 2 diabetes. Drugs not covered and their covered alternatives . Januvia alternatives Biguanides. JANUVIA no debe utilizarse en pacientes con diabetes tipo 1. Important Limitations of Use: Januvia should not be used in patients with type 1 diabetes or for the treatment of diabetic The DPP-4 inhibitor from Merck, which wasHow Does Linagliptin Compare With Other DPP-4 Inhibitors?Linagliptin is the latest addition to the buy cialis online usa array of medications available to treat type 2 diabetes. 2023 Oregon Medicaid formulary (PDF). Continue reading >>, Januvia tradjenta conversion januvia einnahme [23] The clearance by the kidneys is lower, januvia contraindications as kidney function has not fully developed. Given in combination with metformin, linagliptin, saxagliptin, sitagliptin, and vildagliptin showed an equivalent effect whereas alogliptin did not satisfy the equivalence criterion. Januvia (sitagliptin) is an oral drug that reduces blood sugar (glucose) levels in patients with type 2 diabetes. Amicar tranexamic acid, aminocaproic acid: Amrix cyclobenzaprine 5 mg, 10 mg. This medication is supposed to be taken orally, and can be taken with or without food. The recommended dose of Tradjenta is 5 mg once daily. The most common side effects are cough, cold, low blood sugar, and diarrhea. Visit your doctor or health care professional for regular checks on your progress. The clinical material was obtained from a systematic review on this topic. It is unsuitable for anyone with liver, kidney, or heart problems. Use shared decision-making for patients aged 60-69 if 10% risk over 10 years. The manufacturer submitted a cost-minimization analysis 1 comparing alogliptin (6.25 mg, 12.5 mg, or 25 mg) with other DPP-4 inhibitors (linagliptin 5 mg, saxagliptin 5 mg, and sitagliptin 100 mg), in patients with type 2 diabetes mellitus over a one-year time frame. Symptoms may include feeling unwell, muscle pain, difficulty breathing, stomach pain, and sleepiness. See additional information. Bliard Veillard R, Pinto B. DPP-IV Inhibitors [Internet]. Digoxin: oral sitagliptin caused small (11%) increase in AUC and plasma Cmax (18%) of digoxin at 0.25 mg/day. Can be taken with or without food. Indications Indications for It has helped focus the mind, januvia tradjenta conversion as has a strong mutual dislike of each other, which was fuelled in part by being attracted to the same man, ATP Tour heart throb Grigor Dimitrov. Type 2 Diabetes: Signs, Symptoms, Treatments. Type 2 Diabetes Learn More About Type 2 Diabetes Type 1 Diabetes Type 1 diabetes is an autoimmune disorder in which a person's own immune system attacks and destroys the beta cells in the pancreas that make insulin. Images from this publication. DPP-4 inhibitors can also be added to patients already on metformin, sulfonylureas, thiazolidinediones, or insulin. US Brand Name Januvia Descriptions Sitagliptin is used alone or together with other medicines (eg, insulin, glimepiride, metformin, or pioglitazone) and with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. If you need further assistance, please contact Support. RxList does not provide medical advice, diagnosis or treatment. It is unknown if this drug passes into breast milk. Januvia contains the ingredient sitagliptin. It also decreases, (sugar) production in the liver and increases the bodys response to insulin (insulin helps control, s used along with diet and exercise to improve, control in adults and children (10 years or older) with T2D. Only therapeutic interchanges approved by the medical executive committee are allowed. DPP-4 inhibitors ( Januvia, Onglyza, Tradjenta, Nesina) and the newer SGLT-2 inhibitors ( Invokana, Farxiga, Jardiance) are already used for managing type 2 diabetes, and combining them is an opportunity to further improve glucose control and increase convenience for patients. Januvia is a prescription medication used along with diet and exercise to improve blood glucose (blood sugar) control in adults with Type 2 diabetes (T2D, also known as Type 2 diabetes mellitus). [2] Inhibitors of DPP-4 have long been sought as tools to elucidate the functional significance of the enzyme . Treato does not provide medical advice, diagnosis or treatment. Januvia equivalent to tradjenta. Select Try/Buy and follow instructions to begin your free 30-day trial. Januvia and Tradjenta, when used under the care of physicians, have been shown to manage high blood sugar and treat type 2 diabetes. Can be taken with or without food. Glucagon-like peptide 1-based therapies for the treatment of type 2 diabetes mellitus Management of persistent hyperglycemia in type 2 diabetes mellitus medication is required, we prefer a short-acting, low-dose sulfonylurea (eg, glipizide), repaglinide, linagliptin, or cautious use of a GLP-1 receptor agonist or insulin. Saxagliptin: hepatic metabolism; 60% renal and 22% fecal excretion; dialyzable, with 23% removed. Common and serious. Linagliptin, an orally administered DPP-4 inhibitor, has demonstrated favorable efficacy/safety in clinical trials. Januvia: Tradjenta: Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar.Tradjenta Dosage Guide Drugs.comDetailed dosage guidelines and administration information for Tradjenta (linagliptin). is best for you. Saxagliptin: AUC is increased by 27% when saxagliptin is given with a meal compared to fasted conditions. Sitagliptin + metformin: co-formulated as Janumet 50/500 mg twice a day, with meals. Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. DOSING IN SPECIAL POPULATIONS RENAL Sitagliptin GFR 50 mL/min, no dosage adjustment needed GFR 30-50 mL/min, do not exceed 50 mg daily GFR < 30 mL/min, do not exceed 25 mg daily For patients on hemodialys Discuss with your healthcare provider what kind of diet plan is best for you. 2.5/1000 mg, 5/1000 mg, or 5/2000 mg once daily with evening meal. The adult dosage is 1.2 or 1.8 mg SQ every day. After slowly increasing the dose over several weeks, a typical daily dosage of metformin for adults is 850 or 1000 mg twice daily with meals. 43% of reviewers reported a positive effect, while 36% reported a negative effect. Pregnancy may cause or worsen diabetes. Educate patients on side effects and proper use. Most patients (58.4%) had T2DM diagnosis for >5 years; approximately 75% were receiving 1 type of background therapy in addition to linagliptin/placebo. . 2023 Kaiser Permanente Northwest Self . . Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Always consult your doctor or pharmacist. If you have specific questions regarding a drugs safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information. Suggest auto-refill or refill reminder programs. It also decreases glucose (sugar) production in the liver and increases the bodys response to insulin (insulin helps control blood sugar). Liver X Receptor Modulators: Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulator Patients with inadequate glycemic control on this dose of metformin can be titrated gradually, to reduce gastrointestinal side effects associated with metformin, up to the maximum recommended daily dose. 10 mg Dosing Glycemic control in type 2 diabetes CrCl 45 ml/min Starting: 5 mg once daily Maintenance: 5 - 10 mg once daily Maximum: 10 mg once daily May take without regard to food CrCl 25 - 44 ml/min Dapagliflozin is not likely to improve glycemic control in patients with CrCl < 45 ml/min CrCl < 25 ml/min Continue reading >>, Diabetes Cancer COPD Alzheimer's Hepatitis C Treato does not review third-party posts for accuracy of any kind, including for medical diagnosis or treatments, or events in general. Januvia ( sitagliptin) and Tradjenta (linagliptin) are oral diabetes medicines for people with type 2 diabetes (non- insulin -dependent) diabetes. A Johns Hopkins Guides subscription is required to, http://clinicaltrials.gov/ct2/show/NCT01107886, http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm460238.htmComments, Key Studies in Diabetes Care: Efficacy of Therapies, Inhibits dipeptidyl peptidase IV (DPP-IV) enzyme, which prolongs the action of the. AU - Pinto,Brian,Pharm.D. Ozempic has an average rating of 5.8 out of 10 from a total of 772 ratings on Drugs.com. The recommended dose of TRADJENTA is 5 mg once daily. Linagliptin: 5 mg once a day. Health care professionals should consider DPP-4 inhibitors as a possible cause of severe joint pain and discontinue the drug if appropriate. The dose of Tradjenta is 5 mg by mouth daily. Many people using Januvia do not have serious side effects. However, according to the American Diabetes Association (ADA), when considering a vitamin or supplement, you have to consider drug interactions as well as potential effects on your blood sugar. Rarely, it may cause joint pain, skin reactions, pancreatitis, or an allergic. It is categorized in a drug class called, helping the body make more insulin, which helps move sugar from the blood into the tissues, where it can be used for energy. Metformin is a generic drug. It is not known if Victoza causes thyroid cancer in humans. Can be taken with or without food. 436 en la categora de Salud > Farmacia y la nm. Compare Tradjenta vs. Onglyza Head-to-head comparisons of medication uses, side effects, ratings, and more. for adults is 850 or 1000 mg twice daily with meals. Sitagliptin is available in 3 dose strengths: 100 mg, 50 mg, and 25 mg. The side effects featured here are based on those most frequently appearing in user posts on the Internet. Comment: The TECOS Study was done in patients with type 2 diabetes and known cardiovascular disease, and showed that taking sitagliptin for 3 years did not increase or decrease the risk of major adverse cardiovascular events or hospitalization for heart failure. 24/7 Customer Support. Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph. Like Januvia, Tradjenta (linagliptin) is in the DPP-4 inhibitor class of diabetes drugs. The primary difference between this drug and sitagliptin is that saxagliptin comes in 2 dose. The dose of JANUMET XR should be individualized on the basis of the patient's current regimen, effectiveness, and tolerability while not exceeding the maximum recommended daily dose of 100 mg sitagliptin and 2000 mg metformin. Januvia contains the active drug sitagliptin, and Tradjenta contains the active drug linagliptin. De Diego-Sastre JI, Prim-Espada MP, Fernandez-Garcia F. It is now used mainly topically because of renal toxicity and ototoxicity (to hearing). Januvia is not suitable for the treatment of type 1 diabetes and should not be taken by people with diabetic . Another difference is the presence of minerals or other . Scirica BM, Bhatt DL, Braunwald E, et al. Safety data for once-daily linagliptin 5 mg (1 study of linagliptin 2.5 mg twice daily) were analyzed from 22 randomized, double-blind, Phase IIII, placebo-controlled clinical trials of 102 weeks duration. Considering the most recent therapeutic guidelines, our results are of interest particularly as regards the information on DPP-4 inhibitors in combination with metformin. Can be taken with or without food. Sitagliptin: 87% bioavailability; time to peak concentration 1-4 hours. brand name preparation manufacturer route form dosage^ cost* Januvia sitagliptin phosphate Merck oral tablet 25 mg $885 for 90 tabs oral tablet 50 mg $885 for 90 tabs oral tablet 100 mg $295 for 30 tabs Onglyza saxagliptin Bristol-Myers Squibb oral tablet 2.5 mg $295 for 30 tabs oral tablet 5 mg $885 for 90 tabs Tradjenta linagliptin Eli Lilly oral tablet 5 mg $870 for 90 tabs Janumet sitagliptin phosphate + metformin hydrochloride Merck Sharp & Dohme Corp. oral tablet 50/500 mg $885 for 180 tabs oral tablet 50/1000 mg $885 for 180 tabs Nesina alogliptin Takeda oral tablet 6.25 mg $374 for 30 tabs oral tablet 12.5 mg $374 for 30 tabs oral tablet 25 mg $374 for 30 tabs **Patient Assistant Programs: ** Information gathered by Heather Tran and Gladimir Elysee *Prices represent cost per unit specified, are representative of "Average Wholesale Price" (AWP). 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