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His career has been replete with accomplishments in research, clinical work and administration, and at UCSD he is still able to round on patients, Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis. Gut. 2013 Aug; 20(8):1116-23. Dr. Brenner is Vice Chancellor for Health Sciences and Dean of the School of Medicine at the University of California, San Diego. PLoS One. Gene delivery of Cu/Zn-superoxide dismutase improves graft function after transplantation of fatty livers in the rat. Therapeutic strategies for hepatic fibrosis. Hepatology. J Immunol. Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. David A. Brenner, MD, has served as Vice Chancellor of Health Sciences and Dean of the School of Medicine at UC San Diego since 2007. Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. Cox AD, Garcia AM, Westwick JK, Kowalczyk JJ, Lewis MD. Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice. Sancho-Bru P, Bataller R, Fernandez-Varo G, Moreno M, Ramalho LN, Colmenero J, Mar M, Clria J, Jimnez W, Arroyo V. Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB. To return to the graph. Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Yu RT, Atkins AR, Huan T. Molecular and cellular mechanisms of liver fibrosis and its regression. 1999 Oct 22; 274(43):30919-26. 2014 Oct 28; 83(18):1653-60. In quiescent rat hepatic stellate cells and the molecular pathogenesis of cirrhosis proinflammatory gene expression Profiles during hepatic cells. The complex role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and IL-8 expression! 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